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Why You’ll Love This Recipe

This Blueberry Cream Cheese loaf is the ultimate comfort bake, combining a tender, buttery blueberry cake with a hidden layer of rich, tangy cheesecake right in the middle. It’s a total crowd-pleaser that feels much more fancy than a standard quick bread, making it perfect for a cozy weekend breakfast or a “thank you” gift for a neighbor.
Ingredients
- All-purpose flour – This is the foundation of our loaf. I always set aside a small spoonful to toss with the berries; this little trick creates a bit of “grip” so the blueberries stay scattered throughout the batter rather than sinking to the bottom.
- Blueberries – Fresh, plump berries are my favorite here, but frozen work perfectly too! If you use frozen, don’t thaw them first—just fold them in straight from the freezer to keep the batter from turning grey.
- Cream Cheese – You’ll want the classic brick-style cream cheese for that signature velvety ribbon. It adds a decadent richness that balances the sweetness of the berries.
- Sour Cream – This is my “secret weapon” for a moist, tender crumb. It adds a lovely weight to the cake that makes it feel like it came from a professional bakery.
- Vanilla Extract – I use a generous pour of pure vanilla to enhance the sweetness of the fruit and give the cream cheese filling that classic “cheesecake” aroma.
- Pantry Staples – You will also need unsalted butter (make sure it’s softened!), granulated sugar, eggs, baking powder, and a pinch of salt.
Tools and Preparation
- Loaf Pan – A standard 9×5-inch pan is the perfect size for this recipe.
- Parchment Paper – I like to line my pan with parchment paper, leaving a bit hanging over the sides like “handles” so I can lift the whole loaf out cleanly.
- Electric Mixer – Using a hand mixer for the cream cheese layer ensures it is completely smooth and lump-free.
- Rubber Spatula – Essential for gently folding in the berries so they don’t burst before they hit the oven.
- Oven Setup – Preheat your oven to 350°F (175°C) and make sure your rack is positioned in the center for even baking.
Step-by-Step Instructions

- Prep the Berries: In a small bowl, toss your blueberries with about a tablespoon of flour until they are lightly coated. This simple step is the best way to ensure you get blueberries in every single bite!
- Cream the Butter and Sugar: In a large mixing bowl, beat the softened butter and sugar together until the mixture looks pale and fluffy. Add the eggs one at a time, followed by the sour cream and vanilla, mixing until just combined.
- Mix the Dry Ingredients: Gradually stir in the flour, baking powder, and salt. Be careful not to over-mix here—as soon as the white streaks of flour disappear, put the mixer away and gently fold in those floured blueberries with your spatula.
- Make the Cream Cheese Ribbon: In a separate medium bowl, beat the softened cream cheese, a bit of sugar, and one egg until the mixture is silky and smooth. This creates that delicious “cheesecake” center.
- Layer the Batter: Spread about two-thirds of your blueberry batter into the bottom of the prepared pan. Pour the cream cheese mixture over the top, spreading it out toward the edges.
- The Final Layer and Swirl: Spoon the rest of the blueberry batter over the cream cheese in large dollops. Use a butter knife to gently swirl the layers together. Just a couple of “S” shapes will do—you want to keep those distinct pockets of cream cheese!
- Bake: Pop the pan into the oven at 350°F (175°C) for 55–65 minutes. It’s done when the top is golden brown, and a toothpick inserted into the cake part comes out clean.
- Cool Completely: This is the most important part! Let the loaf cool in the pan for 20 minutes, then move it to a wire rack. You really need to wait until it’s fully cool to slice it, or the cream cheese ribbon will be too soft.

Variations
- Add a Topping: For a bit of crunch, sprinkle a quick streusel made of flour, brown sugar, and butter over the top before baking.
- Glazed Delight: Whisk together 1 cup of powdered sugar and a tablespoon of milk to drizzle over the loaf once it’s cool.
- Mixed Berry: Feel free to swap half of the blueberries for raspberries or chopped strawberries for a “triple berry” version.
- Spice it Up: Add 1/2 teaspoon of ground cinnamon to the dry ingredients for a warm, cozy flavor profile.
Storage
- Fridge: Because of the cream cheese filling, this loaf needs to stay chilled. Store it in an airtight container in the refrigerator for up to 5 days.
- Freezing: This recipe freezes beautifully! I like to slice it first, wrap each slice in plastic wrap, and store them in a freezer bag. Then you can just pull out one slice at a time and let it thaw for a quick snack.
Common Mistakes to Avoid
- Cold Cream Cheese: If your cream cheese is cold, it won’t blend smoothly, and you’ll end up with little white lumps in your loaf. Make sure it’s nice and soft before you start.
- Over-mixing: Mixing the batter too much once the flour is added will make the loaf tough and “bready” rather than light and cake-like.
- Skipping the Flour Toss: If you don’t toss the berries in flour, they will all settle at the very bottom of the pan, which can make the base of the loaf soggy.
Final Thoughts
This Blueberry Cream Cheese Loaf is one of those recipes that always gets requested again and again. It’s perfectly sweet, incredibly moist, and that cream cheese center is a total game-changer. Whether you’re serving it for brunch or as a dessert, it’s sure to be the star of the table.
Happy baking!